Le virus de la rougeole - Un futur traitement en canc. Harrington. 11. The Institute of cancer research, division of cancer biology, targeted therapy laboratory, 2. Fulham road, London SW3 6. JB, Royaume Uni. Institut des maladies de l’appareil digestif, Inserm U9. Le virus de la rougeole est l’un des plus contagieux. De plus, la rougeole peut. Le virus de la rougeole est un virus Nantes, 1, place Alexis Ricordeau, 4. Nantes Cedex 1, France. R. Par ailleurs, nous montrerons comment des strat. Attenuated strains are used in immunization with very good safety records. Les virus de la rougeole font partie de la famille des Paramyxoviridae et du genre. Le virus de la rougeole provoque une diminution du. L'infection par le virus de la rub Le virus de la rougeole est un virus envelopp. Interestingly, following clinical observations of tumor regressions after measles infection, preclinical and clinical studies have highlighted the therapeutic potential of attenuated strains of measles. The aim of this review is to explain how these viruses can selectively infect and kill cancer cells, and how this selectivity can be improved. We will detail the therapeutic strategies under development, in particular the combination of viruses with chemotherapy and radiation therapy. Furthermore, the engineering of measles viruses encoding the sodium/iodide symporter could enable virus- directed radio- isotope therapy. Antiviral immunity could be a limit of measles therapy. We will highlight the promising combinations with immunosuppressive drugs and innovative strategies using infected cell carriers, aiming at circumventing the immune response and paving the way to future clinical trials.
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December 2016
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